World's first non-steroidal birth control pill

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World's first non-steroidal birth control pill

Laura 0 11

챗솔루션 Population management is essential for any country. India's population stands second in the APP 개발회사 world and is growing rapidly. Oral contraceptives are preferred choice for birth control/family 재능마켓 planning in women as it prevents the undesired or unwanted pregnancy. The oral 마케팅 스토어 contraceptives available are hormone (steroids) based and may interfere in the normal hormonal 프로그램 스토어 signalling as they need to be consumed daily.CSIR-Central Drug Research Institute's (CSIR-CDRI) developed 개발업체 centchroman/ormeloxifene, which is non-hormonal (non-steroid based) in nature and is consumed once a 실행사 week. There are several advantages of Chhaya/Saheli over hormonal oral contraceptives. Chhaya/Saheli has DB추출기 no side effects like vomiting, nausea, and weight gain. In addition, it can 몽키VPN be taken by women of all ages (Reproductive age) and is also considered 스마트폰콜백 safe for use among breastfeeding women. This makes Chhaya/Saheli a better choice among 마케팅 전문가 all oral contraceptives for family planning.The development of Chhaya/Saheli goes back to the VPN 1960s when responding to the Government of India's need for an effective family 가상 컴퓨터 planning/birth control pill indigenously, CSIR-CDRI, Lucknow took upon the task to develop the 마케팅프로그램 indigenous non-hormonal contraceptive pills. Dr. Nitya Anand and his team at CSIR-CDRI embarked 마케팅기업 on the journey to develop the pill.Among several chemicals/compounds, Centchorman (Ormeloxifene) was derived 마케팅 프로그램 from benzofuran and ethamoxytriphetol (alias MER-25) compounds as an orally taken birth control/family 채팅솔루션 planning drug after several years of perseverance and hard work of Dr. Nitya 채팅앱개발 Anand &ampteam in 1971. The Centchroman was tested in laboratory experimental animals, rats, 무료콜백문자 dogs, and monkeys for preclinical (before human use) contraceptive purposes. Further, the preclinical 앱스토어 검색 harmful effects/toxicity have also been tested on laboratory experimental animals such as rats, 플레이스토어 검색 beagle dogs, rhesus monkeys, and rabbits and found safe.There were several clinical trials 콜백문자서비스 (safety of a drug or chemical) in women before it was approved for NEW DB general population use by the then competent authority of India Drug Regulatory Guideline 가상 윈도우 in 1990. Clinically, 30mg once in a week Saheli/Chhaya (centchroman drug) pill efficacy 프로그램 was tested in women. In the Phase-I clinical trials of centchroman/ormeloxifene, single or VPN 서비스 multiple-dose investigations were conducted in healthy women volunteers as per the Drug Regulatory 앱부스터 Guidelines. They were found very useful without any side effects. After that, dose-ranging 화상채팅 studies and clinical trials were conducted in healthy women with regular monthly periods/ 앱개발 menstrual cycles. For the once-in-a-week dose calculation, a total of about 1000 volunteers 개발회사 were involved for nearly 7000 months/monthly cycle (total) of use. Saheli/centchroman/ormeloxifene use at 일반채팅 30 mg weekly dose demonstrated best contraceptive efficacy without any significant side effects 마케팅 VPN except the delayed menstrual/monthly cycles in 8% healthy volunteers, but the delayed monthly 콜백문자 cycle was normalized while continuing the use of Saheli.Subsequently, during 1981-1982 Phase-III multicentric 영업문자 clinical trial for 30 mg once a week dose was conducted with 909 마케팅프로그램 women volunteers of reproductive age with 1 or 2 living children in 5 마케팅프로그램 Family Welfare Centres in Lucknow and 07 Medical Colleges in the State of 앱솔루션 Uttar Pradesh. The participants/volunteers have been covered for 12828 months and 11448 monthly 마케팅스토어 cycles with acceptable pregnancy protection (Pearl Index: 3.76). The Pearl Index is a 문자명함 statistical estimation of the number of unintended pregnancies in 100 women in a 영업디비 year of exposure to contraceptive pills. The lower pearl index is considered better. 가상 윈도우 컴퓨터 During clinical trials, no adverse effect was seen except that the women's monthly 어플제작 /menstrual cycle was delayed (~45days) in only 8 % of cases, but was 게임 VPN restored to normal in due course in response to drug discontinuation.Phase-II/III trial's assessment 게임IP in over 2000 women participants/ volunteers of reproductive age who have used Saheli/Chhaya/Centchroman VPN 서비스 for about 25000 months showed the acceptable pregnancy protection with Saheli 30 mg DB프로그램 weekly or higher doses and 30 mg biweekly-cum-weekly dose schedule. Thus, the 30 자동콜백 mg biweekly-cum-weekly dose of Saheli/Chhaya/ Ormeloxifene/Centchroman schedule was suggested for pregnancy protection and 마케팅 서비스 cycle control and therefore has been recommended for wider clinical use with DCGI 스마트문자 permission.The contraceptive action of the active ingredient of Saheli /Chhaya, centchroman, causes asynchrony 원격 컴퓨팅 in preparing the uterus (Womb) for the blastocyst implantation, which is otherwise required 채팅어플 for pregnancy/conception. The Saheli/Chhaya gives an edge over the other contraceptives or birth VPN control pills consumed once a week and non-hormonal (Steroidal). HLL launched the Saheli/Chhaya 마케팅IP in 1991. Centchroman has been in the market for over 30 years and 영업 more development has taken place in CSIR-CDRI.After the clinical trials, Saheli (Centchroman) was 앱개발 launched in 1995 in the National family program and is available free of 프로그램스토어 cost at the primary health care centre and the various pharmacy stores all 자동문자 over India. In 2016, the Ormeloxifene/Centrchroman as Chhaya has been reintroduced as part 온라인 마케팅 of "National Family Planning Programme and distributed or delivered home-to-home by 'ASHA' NGOs.CSIR-CDRI, 앱마케팅 in collaboration with Cipla Ltd., Mumbai is planning to explore the possibility of 채팅어플제작 bringing a new generation of ormeloxifene/centchroman (Saheli) with enhanced efficacy and at a 아이피 변경 lower dose. Drs. Rajesh Kumar Jha, Arun K. Trivedi and Sanjeev YadavCentchroman TeamCSIR-Central Drug Research Institute, Lucknow

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